Collective behavior of magnetic microrobots through immuno-sandwich assay: On-the-fly COVID-19 sensing
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F22%3A00568185" target="_blank" >RIV/60077344:_____/22:00568185 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22310/22:43924077 RIV/00027162:_____/22:N0000009 RIV/60461373:22350/22:43924077 RIV/60076658:12310/22:43905040 RIV/62156489:43210/22:43920985
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2352940721003875?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2352940721003875?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.apmt.2021.101337" target="_blank" >10.1016/j.apmt.2021.101337</a>
Alternative languages
Result language
angličtina
Original language name
Collective behavior of magnetic microrobots through immuno-sandwich assay: On-the-fly COVID-19 sensing
Original language description
Mobile self-propelled micro/nanorobots are mobile binding surface that improved the sensitivity of many biosensing system by on-the-fly identification and isolation of different biotargets. Proteins are powerful tools to predict infectious disease progression such as COVID-19. The main methodology used to COVID-19 detection is based on ELISA test by antibodies detection assays targeting SARS-CoV-2 virus spike protein and nucleocapside protein that represent an indirect SARS-CoV-2 detection with low sentitivy and specificity. Moreover ELISA test are limited to used external shaker to obtain homogenously immobilization of antibodies and protein on sensing platform. Here, we present magnetic microrobots that collective self-assembly through immuno-sandwich assay and they can be used as mobile platform to detect on-the-fly SARS-CoV-2 virus particle by its spike protein. The collective self-assembly of magnetic microrobots through immuno-sandwich assay enhanced its analytical performance in terms of sensitivity decreasing the detection limit of SARS-CoV-2 virus by one order of magnitude with respect to the devices previously reported. This proof-of-concept of microrobotics offer new ways to the detection of viruses and proteins of medical interest in general.(c) 2021 Elsevier Ltd. All rights reserved.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20503 - Textiles; including synthetic dyes, colours, fibres (nanoscale materials to be 2.10; biomaterials to be 2.9)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Materials Today
ISSN
2352-9407
e-ISSN
2352-9407
Volume of the periodical
26
Issue of the periodical within the volume
MAR
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
15
Pages from-to
101337
UT code for WoS article
000784043100001
EID of the result in the Scopus database
2-s2.0-85122311148