In-depth Temporal Transcriptome Profiling of Monkeypox and Host Cells using Nanopore Sequencing
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00574489" target="_blank" >RIV/60077344:_____/23:00574489 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/23:00130853 RIV/00027162:_____/23:N0000051
Result on the web
<a href="https://www.nature.com/articles/s41597-023-02149-4" target="_blank" >https://www.nature.com/articles/s41597-023-02149-4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41597-023-02149-4" target="_blank" >10.1038/s41597-023-02149-4</a>
Alternative languages
Result language
angličtina
Original language name
In-depth Temporal Transcriptome Profiling of Monkeypox and Host Cells using Nanopore Sequencing
Original language description
The recent human Monkeypox outbreak underlined the importance of studying basic biology of orthopoxviruses. However, the transcriptome of its causative agent has not been investigated before neither with short-, nor with long-read sequencing approaches. This Oxford Nanopore long-read RNA-Sequencing dataset fills this gap. It will enable the in-depth characterization of the transcriptomic architecture of the monkeypox virus, and may even make possible to annotate novel host transcripts. Moreover, our direct cDNA and native RNA sequencing reads will allow the estimation of gene expression changes of both the virus and the host cells during the infection. Overall, our study will lead to a deeper understanding of the alterations caused by the viral infection on a transcriptome level.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientific Data
ISSN
2052-4463
e-ISSN
2052-4463
Volume of the periodical
10
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
262
UT code for WoS article
001001297200001
EID of the result in the Scopus database
2-s2.0-85158940291