Monoclonal antibodies neutralizing circulating SARS-CoV-2 variants of concern
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00576962" target="_blank" >RIV/60077344:_____/23:00576962 - isvavai.cz</a>
Alternative codes found
RIV/68378050:_____/23:00576962
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/epdf/10.1002/eji.202370200" target="_blank" >https://onlinelibrary.wiley.com/doi/epdf/10.1002/eji.202370200</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Monoclonal antibodies neutralizing circulating SARS-CoV-2 variants of concern
Original language description
Variants of the SARS-CoV-2 virus emerge while it circulates within human population. They carry mutations mostly localized to the Spike protein, which drives viral entry into mammalian cells, and thus allow the virus to escape the neutralizing activities of the host’s immune system. The repeated emergence of the variants raised concern about the activities of current vaccines and therapeutic antibodies, some of which have shown drastically reduced efficacy.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů