Guanine quadruplexes in the RNA genome of the tick tick-borne encephalitis virus: their role as a new antiviral target and in virus biology

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00599752" target="_blank" >RIV/60077344:_____/24:00599752 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/24:00599752 RIV/61388963:_____/24:00599752
Result on the web
<a href="http://www.ccsss.cz/index.php/ccsss/issue/view/48" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/48</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Guanine quadruplexes in the RNA genome of the tick tick-borne encephalitis virus: their role as a new antiviral target and in virus biology
Original language description
Guanine quadruplexes (G4s) are non-canonical secondary structures in nucleic acids1,2. This study identified seven potential G4-forming sequences within the RNA genome of the tick-borne encephalitis virus (TBEV), specifically located in the C, NS1, NS4b, and NS5 genes, as well as the 3′-UTR (ref.3). Biophysical methods confirmed the ability of five of these sequences to form stable monomolecular G4 structures. All the G4s observed were parallel-stranded.
Czech name
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Czech description
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Project
<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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