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The influence of antidotal treatment of low-level tabun exposure on cognitive functions in rats using a water maze

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F06%3A00001486" target="_blank" >RIV/60162694:G44__/06:00001486 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The influence of antidotal treatment of low-level tabun exposure on cognitive functions in rats using a water maze

  • Original language description

    While atropine alone caused an impairment of studied cognitive functions, the addition of an oxime to atropine contributes to the improvement of cognitive performance of treated tabun-poisoned rats regardless of the type of oxime. Therefore, each low-level nerve agent exposure should be treated by complex antidotal treatment consisting of anticholinergic drug and oxime.

  • Czech name

    Vliv antidotní terapie expozice nízké dávce tabunu na kognitivní funkce potkana pomocí vodního bludiště

  • Czech description

    Zatímco samotný atropin vyvolal zhoršení sledovaných kognitivních funkcí, přidání oximu k atropinu vedlo ke zlepšení kognitivních funkcí tabunem intoxikovaných potkanů bez ohledu na typ oximu. To znamená, že každá expozice nízké hladině NPL by měla být léčena komplexní antidotní terapií obsahující atropin a oxim.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/OBVLAJEP20032" target="_blank" >OBVLAJEP20032: C-AGENTS - Medical problem of human being, animal andplant protection against topical types of military useable chemical agents</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neurotoxicity Research

  • ISSN

    1029-8428

  • e-ISSN

  • Volume of the periodical

    9

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    39-45

  • UT code for WoS article

  • EID of the result in the Scopus database