Effect of five acetylcholinesterase reactivators on tabun intoxicated rats: induction of oxidative stress versus reactivation efficacy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F09%3A00002135" target="_blank" >RIV/60162694:G44__/09:00002135 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Effect of five acetylcholinesterase reactivators on tabun intoxicated rats: induction of oxidative stress versus reactivation efficacy
Original language description
Oxime reactivators HI-6, obidoxime, trimedoxime, K347 and K628 were investigated as drugs designed for treatment of tabun intoxication. The experiments were performed on rats in order to simulate real conditions. Rats were intoxicated with one LD50 of tabun and treated with atropine and mentioned reactivators.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
<a href="/en/project/OVUOFVZ200811" target="_blank" >OVUOFVZ200811: Determination of important pharmacokinetic and biochemical parameters and evaluation of blood-brain barrier penetration using drugs introduced to Czech Army</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Applied Toxicology
ISSN
0260-437X
e-ISSN
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Volume of the periodical
29
Issue of the periodical within the volume
6
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
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UT code for WoS article
000269333800004
EID of the result in the Scopus database
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