Antimicrobial activity of extracts and isoquinoline alkaloids of selected papaveraceae plants

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F14%3A65375" target="_blank" >RIV/60460709:41210/14:65375 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11160/14:10289765 RIV/00027014:_____/14:#0002130

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Antimicrobial activity of extracts and isoquinoline alkaloids of selected papaveraceae plants

Original language description

Alkaloidal extracts of seven selected plants of the family Papaveraceae were studied with respect to their activity against six strains of pathogenic bacteria and their alkaloidal fingerprint. Twenty-four alkaloids were determined by GC/MS, and twenty ofthem identified from their mass spectra, retention times and retention indexes. In the antibacterial assay, three Gram-positive (Enterorococcus faecalis, Staphylococcus aureus and S. hyicus), and three Gram-negative (Escherichia coli, Proteus mirabilisand Pseudomonas aeruginosa) strains were used. The most promising antimicrobial activity was shown by the alkaloidal extract of Macleaya cordata with MIC values of 16 ?g/mL for Staphylococcus aureus, 32 ?g/mL for Enterococcus faecalis and 64 ?g/mL for Staphylococcus hyicus and Escherichia coli. All the tested pure isoquinoline alkaloids were considered inactive within the tested concentrations.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Natural Product Communications

ISSN

1934-578X

e-ISSN

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Volume of the periodical

9

Issue of the periodical within the volume

12

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

1709-1712

UT code for WoS article

000346892700011

EID of the result in the Scopus database

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