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Carbon monooxide has ability to delay aging of porcine oocytes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F18%3A78336" target="_blank" >RIV/60460709:41210/18:78336 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Carbon monooxide has ability to delay aging of porcine oocytes

  • Original language description

    Porcine oocytes have to be fertilized shortly after the completion of meiotic maturation. If fertilization does not occure, the oocytes undergo a number of complex undesirable changes called aging. Aging can lead to parthenogenetic activation or apoptosis. Carbon monoxide prodeces by heme oxygenase (HO) has potential to delay aging of porcine oocyte. We found that the inhibition of HO by Zn protoporphyrin IX leads to an increase in the number of apoptic oocytes and decrease in the number of intact oocytes in aging oocytes. Contrarily, the presence of a CO donor CORM-2 significantly decreases the number of apoptic oocytes while increasing the number of intact oocytes.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10604 - Reproductive biology (medical aspects to be 3)

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    10th Workshop on biodiversity, Jevany

  • ISBN

    978-80-213-2910-2

  • ISSN

  • e-ISSN

  • Number of pages

    5

  • Pages from-to

    51-55

  • Publisher name

    neuvedeno

  • Place of publication

    Praha

  • Event location

    Jevany

  • Event date

    Jul 10, 2018

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000464895800010