Effect of different prebiotic saccharides on Listeria monocytogenes adherence to human adenocarcinoma Caco-2 cell line
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F25%3A102296" target="_blank" >RIV/60460709:41210/25:102296 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.3390/cimb47110891" target="_blank" >https://doi.org/10.3390/cimb47110891</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/cimb47110891" target="_blank" >10.3390/cimb47110891</a>
Alternative languages
Result language
angličtina
Original language name
Effect of different prebiotic saccharides on Listeria monocytogenes adherence to human adenocarcinoma Caco-2 cell line
Original language description
Listeria monocytogenes (LM) is one of the most emerging pathogens responsible for the serious foodborne disease listeriosis. The risk of disease outbreaks can be reduced by suppressing the adherence of LM to the intestinal epithelial cells. This effect can be achieved by prebiotic supplementation. The aim of this work was to determine the effect of prebiotics beta-(1,3)-D-glucan, inulin, fructooligosaccharides, galactooligosaccharides, lactulose, raffinose, stachyose, human milk oligosaccharides (HMOs), and 2’-fucosyllactose on the ability of LM to adhere to the human adenocarcinoma Caco-2 cell line. Despite strain-specific variability, a statistically significant reduction in LM adhesion to intestinal epithelial cells was observed in the presence of beta-(1,3)-D-glucan (~60% reduction), inulin (~46%), and HMOs (~44%). In contrast, the remaining tested prebiotics did not show a significant impact on LM adhesion. These findings highlight the potential of specific prebiotics, especially beta-glucans, to limit LM adherence, suggesting a protective effect for the host.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
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Continuities
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Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
CURRENT ISSUES IN MOLECULAR BIOLOGY
ISSN
1467-3037
e-ISSN
1467-3045
Volume of the periodical
47
Issue of the periodical within the volume
11
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
16
Pages from-to
1-16
UT code for WoS article
001625544800001
EID of the result in the Scopus database
2-s2.0-105022910876