Syntheses of phenyl(hydroxy)ethylguanines as biomarkers of exposure to styrene

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F02%3A00006511" target="_blank" >RIV/60461373:22310/02:00006511 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Syntheses of phenyl(hydroxy)ethylguanines as biomarkers of exposure to styrene

Original language description

The most effective approach for the synthesis of 7-N-hydroxy(phenyl)ethylguanines was the alkylation of 2-amino-6-chloropurine by allyl protected synthetic equivalents of styrene 7,8-oxide followed by conversion to guanine derivatives and deprotection. 7-N-hydroxy(phenyl)ethylguanines obtained are used as analytical standards for methods of early diagnosis of DNA damage caused by styrene.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

CC - Organic chemistry

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2002

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Toxicology Letters

ISBN

0378-4274

ISSN

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e-ISSN

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Number of pages

1

Pages from-to

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Publisher name

Elsevier

Place of publication

Brusel

Event location

Budapest, Maďarsko

Event date

Jun 6, 2002

Type of event by nationality

EUR - Evropská akce

UT code for WoS article

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