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Hydroboration of 1,1′-bi(cyclopent-1-ene) and 3,3′-biindene: experimental and theoretical study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F06%3A00017028" target="_blank" >RIV/60461373:22310/06:00017028 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Hydroboration of 1,1′-bi(cyclopent-1-ene) and 3,3′-biindene: experimental and theoretical study

  • Original language description

    Hydroboration of bi(cyclopent-1-ene) (1) or 3,3&#8242;-biindene (2) with borane, thexylborane or (-)-isopinocampheylborane afforded, regardless of reaction conditions, meso-isomers of polycyclic 1,4-diols 3a, 4a as the main products. No reaction was observed with 9-BBN. The structure of the major product 4a, as well as of the minor racemic product 4b was assigned based on 1H NMR spectra of the corresponding Mosher's diesters 5a-5c. Finally, the stereochemistry of the product 4a was confirmed by a single-crystal X-ray analysis of the corresponding dimesylate 6. To elucidate preferential formation of the meso-isomers, complexes of monohydroborated intermediate with borane were studied theoretically by DFT methods.

  • Czech name

    Hydroborace 1,1′-bi(cyklopent-1-enu) a 3,3′-biindenu: experimentální a teoretická studie

  • Czech description

    Hydroborace bi(cyklopent-1-enu) (1) nebo 3,3&#8242;-biindenu (2) s boranem, thexylboranem nebo (-)-isopinokamfeylboranem poskytla bez ohledu na reakční podmínky meso-isomery polycyklických 1,4-diolů 3a, 4a jako hlavní produkty. 9-BBN nereagoval. Struktura hlavního produktu4a a vedlejšího racemického produktu 4b byly určeny pomocí 1H NMR spekter odpovídajících Mosherových diesterů 5a-5c. Stereochemie produktu 4a byla potvrzena krystalografickou analýzou odpovídajícího dimesylátu 6. Za účelem vysvětlení přednostního vzniku meso-isomerů byly komplexy monohydroborovanýchz intermediatů s borany studovány teoreticky pomocí DFT method.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA203%2F03%2F0496" target="_blank" >GA203/03/0496: Chiral 7-bora- and 7-silabicyclo[6.3.0.0]undecanes and their benzo analogues. Syntheses and applications</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Collection of Czechoslovak Chemical Communications

  • ISSN

    0010-0765

  • e-ISSN

  • Volume of the periodical

    71

  • Issue of the periodical within the volume

    11-12

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    16

  • Pages from-to

    1611-1626

  • UT code for WoS article

  • EID of the result in the Scopus database