Evaluation of Functional Characteristics of Lactose by Inverse Gas Chromatography
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F12%3A43894827" target="_blank" >RIV/60461373:22310/12:43894827 - isvavai.cz</a>
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S1877705812028573" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1877705812028573</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.proeng.2012.07.457" target="_blank" >10.1016/j.proeng.2012.07.457</a>
Alternative languages
Result language
angličtina
Original language name
Evaluation of Functional Characteristics of Lactose by Inverse Gas Chromatography
Original language description
The work was focused on the analysis of different batches of the common pharmaceutical excipient lactose using inverse gas chromatography (IGC). Several batches of amorphous (spray dried) and crystalline form of lactose were studied. Surface properties represented by the surface energy and specific (acid-base) interactions between probes and analyzed samples shows batch variations and significant differences between manufacturers and technological processes. The second part of this work was focused on effect of relative humidity and temperature on stability of lactose. The variations of surface energy and specific interactions over time were studied. The changes in surface properties of two batches of lactose-amorphous and crystalline caused by higherrelative humidity were measured by IGC. From measured values are obvious different chemical and physical properties of both lactose forms. Negative effect of higher temperature and air humidity lead to changes in surface energy and mainly
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CI - Industrial chemistry and chemical engineering
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Procedia Engineering
ISSN
1877-7058
e-ISSN
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Volume of the periodical
42
Issue of the periodical within the volume
September
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
7
Pages from-to
644-650
UT code for WoS article
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EID of the result in the Scopus database
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