Absolute configuration of the antimalarial erythro-mefloquine - vibrational circular dichroism and X-ray diffraction studies of mefloquine and its thiourea derivative
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F16%3A43902792" target="_blank" >RIV/60461373:22310/16:43902792 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1039/c6ra19367f" target="_blank" >http://dx.doi.org/10.1039/c6ra19367f</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c6ra19367f" target="_blank" >10.1039/c6ra19367f</a>
Alternative languages
Result language
angličtina
Original language name
Absolute configuration of the antimalarial erythro-mefloquine - vibrational circular dichroism and X-ray diffraction studies of mefloquine and its thiourea derivative
Original language description
The long-standing discussion of the absolute configuration of erythro-mefloquine is revisited, showcasing the strength of a combination of experimental and calculated vibrational circular dichroism spectroscopy. The resulting assignment of one of the most important antimalarials is subsequently confirmed by electronic circular dichroism spectroscopy and X-ray diffraction-based structure elucidation of thiourea derivatives, adding to the amount of evidence on the absolute configuration that had long remained a matter of debate.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JJ - Other materials
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
RSC Advances
ISSN
2046-2069
e-ISSN
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Volume of the periodical
6
Issue of the periodical within the volume
85
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
81461-81465
UT code for WoS article
000382776000001
EID of the result in the Scopus database
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