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Investigating Lubricant Effects on Disintegration Stability of Paracetamol-Caffeine-Phenylephrine Tablets

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F16%3A43902913" target="_blank" >RIV/60461373:22310/16:43902913 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.prolekare.cz/ceska-slovenska-farmacie-clanek/pracovni-den-sekce-technologie-leku-pokroky-v-lekovych-formach-60009" target="_blank" >http://www.prolekare.cz/ceska-slovenska-farmacie-clanek/pracovni-den-sekce-technologie-leku-pokroky-v-lekovych-formach-60009</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Investigating Lubricant Effects on Disintegration Stability of Paracetamol-Caffeine-Phenylephrine Tablets

  • Original language description

    The aim of this work is to report a case study of successful investigation of stability problems caused by excipient-excipient interaction in a combined drug product. The work involves multicomponent mixtures containing the active pharmaceutical ingredients paracetamol, caffeine, and phenylephrine hydrochloride for tablet compression, the physical properties of which exhibited substantial change in physical properties during stability tests combined with significant batch-to-batch variability of the properties.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    JJ - Other materials

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Česká a slovenská farmacie

  • ISSN

    1803-6597

  • e-ISSN

  • Volume of the periodical

    65

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    2

  • Pages from-to

    196-197

  • UT code for WoS article

  • EID of the result in the Scopus database