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6-thioguanine therapy in patients intolerant or refractory to azathioprine or 6-mercaptopurine therapy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F03%3A00008424" target="_blank" >RIV/60461373:22330/03:00008424 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    6-thioguanine therapy in patients intolerant or refractory to azathioprine or 6-mercaptopurine therapy

  • Original language description

    Azathioprine (AZA) and 6-mercaptopurine (6-MP) are effective therapeutic agents in treatment of IBD. However, about 20#35 % of patients are unresponsive and about 15 % of patients develop intolerance to AZA/6-MP. 6-thioguanine (6-TG) is an alternativetherapy to AZA/6-MP in children with acute lymphoblastic leucaemia which gives rise to high 6-TG nucleotides levels # the most active metabolites of AZA/6-MP

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2003

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Biomedical Papers

  • ISBN

    1213-8118

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

    60-60

  • Publisher name

    Univerzita Palackého

  • Place of publication

    Olomouc

  • Event location

    Olomouc

  • Event date

    Oct 2, 2003

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article