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Structural Studies of Tomato Nuclease TBN1

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F09%3A00022157" target="_blank" >RIV/60461373:22330/09:00022157 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Structural Studies of Tomato Nuclease TBN1

  • Original language description

    Bifunctional nuclease TBN1 from Solanum lycopersicum - red tomato belongs to plant nuclease I group. TBN1 is a relatively small glycoprotein and shows considerable activity in cell apoptosis, tissue differentiation and vascular system development. Therefore detailed structural study of this enzyme can lead to new ways of cancer and bacterial disease treatment. Heterologous expression of the enzyme yields amounts and quality of protein suitable for structural studies. Biochemical characterrisation of TBN1 focused on 3D structure determination using crystallographic methods and also crystallization and preliminary X-ray diffraction experiments are reviewed.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA521%2F09%2F1214" target="_blank" >GA521/09/1214: Modification and in planta production of bifunctional nucleases and analysis of their anticancerogenic and biological activities</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Proceedings of the 18th Annual Conference of Doctoral Students - WDS 2009, Part III

  • ISBN

    978-80-7378-103-3

  • ISSN

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

  • Publisher name

    MATFYZPRESS, vydavatelství MFF UK Praha

  • Place of publication

    Praha

  • Event location

    Praha

  • Event date

    Jun 2, 2009

  • Type of event by nationality

    CST - Celostátní akce

  • UT code for WoS article