The immunomodulatory effect of Lactobacillus plantarum strains on mononuclear cells isolated from human peripheral blood.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F14%3A43898386" target="_blank" >RIV/60461373:22330/14:43898386 - isvavai.cz</a>
Alternative codes found
RIV/26722861:_____/14:#HY58
Result on the web
<a href="http://www.academicjournals.org/article/article1410257161_Lisov%C3%A1%20et%20al.pdf" target="_blank" >http://www.academicjournals.org/article/article1410257161_Lisov%C3%A1%20et%20al.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5897/AJMR2014.6744" target="_blank" >10.5897/AJMR2014.6744</a>

Result language
angličtina
Original language name
The immunomodulatory effect of Lactobacillus plantarum strains on mononuclear cells isolated from human peripheral blood.
Original language description
The immunomodulatory effect of nine strains of Lactobacillus plantarum by stimulation of human peripheral blood mononuclear cells (hPBMCs) from healthy donors was investigated. The production of pro-inflammatory, anti-inflammatory and regulatory cytokines by mononuclear cells following exposure of live bacterial cells was measured using multiplex analysis Luminex. The stimulation and production of cytokine by hPBMCs was evaluated to be strain specific and dependent on the density of cells used for stimulation. A significant increase of IL-6 and IL-1beta secretion was demonstrated following stimulation of hPMBCs by high densities of lactobacilli (P { 0.05). By contrast, low density of lactobacilli strains increased the production of TNF-alfa (P { 0.05)in seven out of nine strains tested. The results have also shown the importance of testing probiotics with using multiplex methods that can help to explanation of the effectiveness/ineffectiveness of probiotics in the treatment and preven
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GM - Food industry
OECD FORD branch
—

Project
<a href="/en/project/QJ1210376" target="_blank" >QJ1210376: Colostrum as a source of new primary products in food and food supplements characterized by improved dietary properties and high content of natural biologically active substances.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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