Tailoring of PEEK bioactivity for improved cell interaction: plasma treatment in action
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F15%3A43899842" target="_blank" >RIV/60461373:22330/15:43899842 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22310/15:43899842 RIV/44555601:13440/15:43886689
Result on the web
<a href="http://dx.doi.org/10.1039/c5ra03861h" target="_blank" >http://dx.doi.org/10.1039/c5ra03861h</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c5ra03861h" target="_blank" >10.1039/c5ra03861h</a>
Alternative languages
Result language
angličtina
Original language name
Tailoring of PEEK bioactivity for improved cell interaction: plasma treatment in action
Original language description
Despite the extensive use of polyetheretherketone (PEEK) in biomedical applications, information about cell adhesion on this biomaterial is limited. This study focuses on PEEK tuned by argon plasma treatment with the aim to enhance its wettability and cytocompatibility. Changes in surface properties of the plasma treated surface were studied in relation to the adhesion, proliferation and metabolic activity of mouse fibroblasts (L929) and human osteoblast (U-2 OS) in vitro. Moreover, the expression profiles of two proteins (talin 1 and vinculin) responsible for cell adhesion, were determined at 2 time points in dependence on the PEEK treatment. Plasma treatment increased the surface wettability of PEEK and led to changes in its surface morphology and chemistry. The XPS method showed a decrease in carbon content and augmentation of oxygen concentration with increasing effect of the plasma. Plasma treatment of PEEK significantly enhanced cell adhesion, proliferation and metabolic activity
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JJ - Other materials
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
RSC Advances
ISSN
2046-2069
e-ISSN
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Volume of the periodical
5
Issue of the periodical within the volume
52
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
41428-41436
UT code for WoS article
000354445900015
EID of the result in the Scopus database
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