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Tailoring of PEEK bioactivity for improved cell interaction: plasma treatment in action

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F15%3A43899842" target="_blank" >RIV/60461373:22330/15:43899842 - isvavai.cz</a>

  • Alternative codes found

    RIV/60461373:22310/15:43899842 RIV/44555601:13440/15:43886689

  • Result on the web

    <a href="http://dx.doi.org/10.1039/c5ra03861h" target="_blank" >http://dx.doi.org/10.1039/c5ra03861h</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1039/c5ra03861h" target="_blank" >10.1039/c5ra03861h</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Tailoring of PEEK bioactivity for improved cell interaction: plasma treatment in action

  • Original language description

    Despite the extensive use of polyetheretherketone (PEEK) in biomedical applications, information about cell adhesion on this biomaterial is limited. This study focuses on PEEK tuned by argon plasma treatment with the aim to enhance its wettability and cytocompatibility. Changes in surface properties of the plasma treated surface were studied in relation to the adhesion, proliferation and metabolic activity of mouse fibroblasts (L929) and human osteoblast (U-2 OS) in vitro. Moreover, the expression profiles of two proteins (talin 1 and vinculin) responsible for cell adhesion, were determined at 2 time points in dependence on the PEEK treatment. Plasma treatment increased the surface wettability of PEEK and led to changes in its surface morphology and chemistry. The XPS method showed a decrease in carbon content and augmentation of oxygen concentration with increasing effect of the plasma. Plasma treatment of PEEK significantly enhanced cell adhesion, proliferation and metabolic activity

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    JJ - Other materials

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    RSC Advances

  • ISSN

    2046-2069

  • e-ISSN

  • Volume of the periodical

    5

  • Issue of the periodical within the volume

    52

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    41428-41436

  • UT code for WoS article

    000354445900015

  • EID of the result in the Scopus database