Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F16%3A43901833" target="_blank" >RIV/60461373:22330/16:43901833 - isvavai.cz</a>
Alternative codes found
RIV/60460709:41210/16:70772 RIV/60460709:41340/16:70772
Result on the web
<a href="http://dx.doi.org/10.1016/j.bjp.2016.03.016" target="_blank" >http://dx.doi.org/10.1016/j.bjp.2016.03.016</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bjp.2016.03.016" target="_blank" >10.1016/j.bjp.2016.03.016</a>
Alternative languages
Result language
angličtina
Original language name
Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
Original language description
Among 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 +/- 51.4 mu g TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative effect (IC50 for Hep-G2 and HT-29 = 2.7 and 9.0 mu g/ml, respectively). However, combinatory antioxidant/anti-proliferative effect was only detected in Oenocarpus bataua Mart., Arecaceae (DPPH = 903.8 and ORAC = 1024 mu g TE/mg extract; IC50 for Hep-G2 and HT-29 at 102.6 and 38.8 mu g/ml, respectively) and Inga edulis Mart., Fabaceae (DPPH = 337.0 and ORAC = 795.7 mu g TE/mg extract; IC50 for Hep-G2 and HT-29 at 36.3 and 57.9 mu g/ml, respectively). Phenolic content was positively correlated with antioxidant potential, however not with anti-proliferative effect. None of these extracts possessed toxicity towards normal foetal lung cells, suggesting their possible use in development of novel plant-based agents with preventive and/or therapeutic action against oxidative stress-related diseases.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GM - Food industry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LD14070" target="_blank" >LD14070: Adhesive properities of probiotics to the intestinal epithelium</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Revista Brasileira de Farmacognosia
ISSN
0102-695X
e-ISSN
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Volume of the periodical
26
Issue of the periodical within the volume
6
Country of publishing house
BR - BRAZIL
Number of pages
10
Pages from-to
728-737
UT code for WoS article
000389621500011
EID of the result in the Scopus database
2-s2.0-85006263965