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Extracellular DNA as a target molecule for biofilm disruption

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F18%3A43915316" target="_blank" >RIV/60461373:22330/18:43915316 - isvavai.cz</a>

  • Alternative codes found

    RIV/60461373:22810/18:43915316

  • Result on the web

    <a href="http://www.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/3063" target="_blank" >http://www.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/3063</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Extracellular DNA as a target molecule for biofilm disruption

  • Original language description

    Biofilm matrix forms a dynamic microenvironment facilitating the resilience of the biofilm. Extracellular DNA (eDNA) is one of the matrix components playing a crucial role in the cell adhesion, aggregation and structure stabilization. Its sticky nature and negative charge reduce the penetration of antimicrobials and further enable the biofilm tolerance or even resistance. The resistance can be encoded in the biofilm matrix genetic information. Moreover, the biofilm matrix with eDNA creates an ideal environment for gene transfer. For all above mentioned reasons, eDNA is a substance with a significant potential for the biofilm disruption in food processing, as well as in medicine. The combination of several different techniques successful in biofilm disruption could facilitate even eradication of the biofilm with various pathogens.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10606 - Microbiology

Result continuities

  • Project

    <a href="/en/project/GA17-15936S" target="_blank" >GA17-15936S: Interaction of nanoparticles modified by natural compounds with biofilms of pathogenic microorganisms</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemické listy

  • ISSN

    0009-2770

  • e-ISSN

  • Volume of the periodical

    112

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    215-221

  • UT code for WoS article

    000430047200003

  • EID of the result in the Scopus database