Molecules Autoinducer 2 and cjA and Their Impact on Gene Expression in Campylobacter jejuni.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F19%3A43920132" target="_blank" >RIV/60461373:22330/19:43920132 - isvavai.cz</a>

Result on the web

<a href="https://www.karger.com/Article/Abstract/495411" target="_blank" >https://www.karger.com/Article/Abstract/495411</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Molecules Autoinducer 2 and cjA and Their Impact on Gene Expression in Campylobacter jejuni.

Original language description

Quorum sensing is a widespread form of cell-to-cell communication, which is based on the production of signaling molecules known as autoinducers (AIs). The first group contains highly species-specific N-acyl homoserine lactones (N-AHLs), generally known as AI-1, which are produced by AHL synthase. The second group, possessing the characteristic structure of a furanone ring, are known as AI-2. The enzyme responsible for their production is S-ribosylhomocysteine lyase (LuxS). In Campylobacter jejuni, AI-2 and LuxS play a role in many important processes, including biofilm formation, stress response, motility, expression of virulence factors, and colonization. However, neither the receptor protein nor the exact structure of the AI-2 molecule have been identified to date. Similarly, little is known about the possible existence of AHL-synthase producing AI-1 and its impact on gene expression. Recently, an analogue of homoserine lactone, called cjA, was isolated from a cell-free supernatant of C. jejuni strain 81-176 and from the food isolate c11. The molecule cjA particularly impacted the expression of virulence factors and biofilm formation. This review summarizes the role of AI-2 and cjA in the context of biofilm formation, motility, stress responses, and expression of virulence factors.

Czech name

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Czech description

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Type

J_ost - Miscellaneous article in a specialist periodical

CEP classification

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OECD FORD branch

10606 - Microbiology

Project

<a href="/en/project/GA18-16549S" target="_blank" >GA18-16549S: The prevalence and diversity of Campylobacter jejuni isolates and identification of factors facilitating their survival</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Molecular Microbiology and Biotechnology

ISSN

1464-1801

e-ISSN

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Volume of the periodical

28

Issue of the periodical within the volume

January

Country of publishing house

CH - SWITZERLAND

Number of pages

8

Pages from-to

207-215

UT code for WoS article

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EID of the result in the Scopus database

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