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DEVELOPMENT OF AN ELISA SYSTEM ON A MICROCHIP PLATFORM

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F04%3A00011209" target="_blank" >RIV/60461373:22340/04:00011209 - isvavai.cz</a>

  • Alternative codes found

    RIV/60461373:22340/04:00013195

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    DEVELOPMENT OF AN ELISA SYSTEM ON A MICROCHIP PLATFORM

  • Original language description

    This work is focused on development of a microdevice for an immunoassay performed on asolid phase. Our efforts cover both the mathematical modeling of realistic microsystems andthe development of experimental procedures for construction of such microdevices.Description of microdevices for the ELISA applications is rarely reported in theliterature. They usually consist of either a layer of microparticles with immobilized antigen orwith an antigen bound on walls of microchannels. None of the reported applications has beencommercially used yet. In addition to high costs, these microdevices have still manydisadvantages such as difficult manipulation with microparticles, low concentration ofantibody at walls with the immobilized antigen, irregularity in thelayer of the immobilizedantigen etc.We propose a system that should minimize these disadvantages. The central part ofthis microdevice contains a porous material. Pores of the material are permeable for smallmolecules and ions. Larger mol

  • Czech name

    Vývoj ELISA systému na mikročipové bázi

  • Czech description

    Práce je zaměřena na vývoj mikrozařízení pro imunoanalýzu na pevném nosiči. Naše snahy zahrnují matematické modelování realistických mikrosystémů a také vývoj experimentálních procedur pro konstrukci takových zařízení. Byl navržen model mikrozařízení proimunoanalýzu, který umožňuje minimalizovat spotřebu drahých reaktantů a zároveň zkoncentrování roztoku u povrchu s vázanými aktivními molekulami.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CI - Industrial chemistry and chemical engineering

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA104%2F02%2F0339" target="_blank" >GA104/02/0339: Nonstationary operation of microreactors</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Proceeding of 31th International Conference of Chemical Engineering, Tatranské Matliare, Slovakia

  • ISBN

    80-227-2052-6

  • ISSN

  • e-ISSN

  • Number of pages

    8

  • Pages from-to

  • Publisher name

    Slovak Society of Chemical Engineering

  • Place of publication

    Bratislava

  • Event location

    Tatranské Matliare

  • Event date

    May 24, 2004

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article