Modeling of immunoassay in a microstructured device
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F04%3A00011214" target="_blank" >RIV/60461373:22340/04:00011214 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22340/04:00013198
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Modeling of immunoassay in a microstructured device
Original language description
Microstructured microdevices such as DNA chips, microcapillary arrays and other devices are widely used in medicine and analytical chemistry. On the other hand, microchips for immunoassay are still in the stage of development, even if the first commercial microdevices for competitive immunoassay were already released on market. These microchips are much more expensive than the standard ELISA kits. Development of ELISA microchip is complicated due to the necessity of antigen or antibody immobilization inmicrostructures. The main aim of this work is development of a proper mathematical description of ELISA microsystems. Results of this work can serve for effective construction of such microdevices. Realistic arrangement of an ELISA microchip is considered. We proposed and discussed three mathematical models of the spatially two-dimensional microchip. These models are based on the molar balances of all compounds of the microchip electrolyte (e.g. antibody, buffer in the electroneutral an
Czech name
Modelování imunoanalýzy v mikrostrukturovaném zařízení
Czech description
Hlavním cílem práce je vývoj vhodného matematického popisu ELISA mikrosystému. Výsledky práce mohou sloužit při konstrukci mikročipů. Jsou studovány vlivy elektrokinetického transportu na průběh imunologické interakce. Byly uvažovány slip okrajové podmínky s nenulovou konvektivní rychlostí u povrchu mikročipu.
Classification
Type
D - Article in proceedings
CEP classification
CI - Industrial chemistry and chemical engineering
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA104%2F02%2F0339" target="_blank" >GA104/02/0339: Nonstationary operation of microreactors</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Proceedings 16th International Congress of Chemical and Process Engineering CHISA 2004
ISBN
80-86059-40-5
ISSN
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e-ISSN
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Number of pages
18
Pages from-to
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Publisher name
Ing. Jan Novosad, Procesní inženýrství
Place of publication
Praha
Event location
Praha
Event date
Aug 22, 2004
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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