The effect of primary particle surface energy on agglomeration rate in fluidised bed wet granulation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F08%3A00020739" target="_blank" >RIV/60461373:22340/08:00020739 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The effect of primary particle surface energy on agglomeration rate in fluidised bed wet granulation

Original language description

The effect of primary particle surface wettability by a binder solution on the rate of agglomeration in a fluid-bed top-spray granulation process was investigated. A model system consisting of hydrophilic and hydrophobic spherical primary particles witha narrow size distribution, and an aqueous solution of hydroxy propyl-cellulose (HPC) as binder, was used. The surface energy of the primary particles was measured by inverse gas chromatography (IGC) and their wettability was characterised by static anddynamic contact angle. Granulation was carried out in a desktop fluid-bed granulator and the resulting granule size distribution and granule microstructure were analysed. The hydrophobic particles gave a wider granule size distribution (larger maximum granule size) than hydrophilic ones under otherwise identical conditions, and the granules were notably rounder and more compact. However, the fraction of un-granulated fines was also higher in the case of hydrophobic primary particles. SEM

Czech name

Vliv povrchové energie primárních částic na rychlost granulace ve fluidní vrstvě

Czech description

Práce jako první přímo ukazuje vztah mezi povrchovou energií a tedy smáčivostí primárních částic a kinetikou jejich granulace ve fluidní vrstvě. Pomocí inverzní plynové chromatografie byl charakterizován povrch částic a bylo dokázáno, že existuje optimální hydrofobní charakter částic, který maximalizuje nárůst granulí. Totéž bylo potvrzeno pomocí počítačové simulace.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CI - Industrial chemistry and chemical engineering

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Powder Technology

ISSN

0032-5910

e-ISSN

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Volume of the periodical

181

Issue of the periodical within the volume

2

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

9

Pages from-to

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UT code for WoS article

000253190200009

EID of the result in the Scopus database

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