A419C polymorphism of glyoxalase I gene: renal function and histological finding at 12 months after renal transplantation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F10%3A00023496" target="_blank" >RIV/60461373:22340/10:00023496 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
A419C polymorphism of glyoxalase I gene: renal function and histological finding at 12 months after renal transplantation
Original language description
Background and Aims: AGEs (advanced glycation end products) are involved in the pathogenesis of vascular damage and progression of chronic kidney diseases. They are detoxified by the glyoxalase (GLO) system. The aim of the study was to test whether A419Cpolymorphism of GLO I gene is associated with the outcome of kidney transplantation. Methods: A419C polymorphism of the GLO I gene was assessed in 145 renal transplant recipients and its relationship to histological changes in 12 months protocol kidneygraft biopsy and renal function was examined. Results: Genotype frequencies of the studied polymorphism corresponded to the expected frequencies according to Hardy-Weinberg equilibrium. No significant differences among allelic and genotype frequencies among patients with normal histological findings, interstitial fibrosis/tubular atrophy and subclinical rejection and renal parameters were found. However, a trend towards lower levels of serum creatinine and proteinuria was observed in pat
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
—
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Nephrology and Urology
ISSN
2008-4684
e-ISSN
—
Volume of the periodical
2
Issue of the periodical within the volume
4
Country of publishing house
IR - IRAN, ISLAMIC REPUBLIC OF
Number of pages
10
Pages from-to
—
UT code for WoS article
—
EID of the result in the Scopus database
—