Effects of Convective Flow On Chemical Signaling in Cellular Systems

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F10%3A00023540" target="_blank" >RIV/60461373:22340/10:00023540 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Effects of Convective Flow On Chemical Signaling in Cellular Systems
Original language description
In this contribution, we will introduce mathematical models of the key processes in such multicellular systems: the growth factor and protease diffusion and convection transport in an extracellular matrix and their release into the matrix, the ligand-receptor binding and simplified intracellular cascades leading to the ligand synthesis. Due to the consideration of the convective transport, these mathematical models significantly extend our insight into the chemical signaling in cellular systems based previously on reaction-diffusion equations. We believe that such mathematical models can be helpful for understanding developmental processes (vascular system formation) and also for understanding of cell motility in tissues (tissue injury, migration of cancer cells). Introductory results will be presented in this contribution.
Czech name
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Czech description
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Project
<a href="/en/project/ME10036" target="_blank" >ME10036: Effects of convective transport on chemical signal propagation in living tissues</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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