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Mathematical modelling of Wurster fluid bed coating

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F18%3A43917278" target="_blank" >RIV/60461373:22340/18:43917278 - isvavai.cz</a>

  • Alternative codes found

    RIV/60461373:22340/19:43919989

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Mathematical modelling of Wurster fluid bed coating

  • Original language description

    Wurster fluid bed coating is an effective way of manufacturing the layers used to create drug delivery systems, but it requires very precise control. On an industrial scale, the optimization of Wurster coating process parameters can be demanding because it necessitates many time-consuming pilot-scale experiments, the scope of which is limited by the cost of APIs. In this presentation we summarize results of our thermodynamic model and show its applicability as an analytical and predictive tool for drug production optimization. In the second part, we discuss possibility to extend the model with results extracted from CFD-DEM simulations.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    20401 - Chemical engineering (plants, products)

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů