In vivo Raman spectroscopy in the diagnostics of colon cancer

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F23%3A43926019" target="_blank" >RIV/60461373:22340/23:43926019 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/23:10465400 RIV/00064165:_____/23:10465400
Result on the web
<a href="https://pubs.rsc.org/en/content/articlelanding/2023/AN/D3AN00103B" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2023/AN/D3AN00103B</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/D3AN00103B" target="_blank" >10.1039/D3AN00103B</a>

Result language
angličtina
Original language name
In vivo Raman spectroscopy in the diagnostics of colon cancer
Original language description
Early detection and accurate diagnosis of colorectal carcinoma are crucial for successful treatment, yet current methods can be invasive and even inaccurate in some cases. In this work, we present a novel approach for in vivo tissue diagnostics of colorectal carcinoma using Raman spectroscopy. This almost non-invasive technique allows for fast and accurate detection of colorectal carcinoma and its precursors, adenomatous polyps, enabling timely intervention and improved patient outcomes. Using several methods of supervised machine learning, we were able to achieve over 91% accuracy in distinguishing colorectal lesions from healthy epithelial tissue and more than 90% classification accuracy for premalignant adenomatous polyps. Moreover, our models enabled the discrimination of cancerous and precancerous lesions with a mean accuracy of almost 92%. Such results demonstrate the potential of in vivo Raman spectroscopy to become a valuable tool in the fight against colon cancer.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry

Project
<a href="/en/project/NU20-09-00229" target="_blank" >NU20-09-00229: The development of novel analytical approaches for early diagnosis of adenomatous polyps and prevention of colorectal carcinoma</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)