Neuroactive pregnanolone isomers during pregnancy

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F05%3A00021343" target="_blank" >RIV/61388963:_____/05:00021343 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/05:00009370 RIV/00064165:_____/05:00001150
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Neuroactive pregnanolone isomers during pregnancy
Original language description
The pregnanolone isomers (PI) allopregnanolone (3alpha-hydroxy-5alpha-pregnan-20-one), pregnanolone (3alpha-hydroxy-5beta-pregnan-20-one), isopregnanolone (3beta-hydroxy-5alpha-pregnan-20-one), epipregnanolone (3beta-hydroxy-5beta-pregnan-20-one), progesterone, and estradiol were measured in 138 pregnant women. All the PI showed a significant increase during pregnancy, which was more pronounced in the 3alpha-steroids.
Czech name
Neuroaktivní isomery pregnanolonu během těhotenství
Czech description
Isomery pregnanolonu - allopregnanolon (3alfa-hydroxy-5alfa-pregnan-20-on), pregnanolon (3alfa-hydroxy-5beta-pregnan-20-on), isopregnanolon (3beta-hydroxy-5alfa-pregnan-20-on), epipregnanolon (3beta-hydroxy-5beta-pregnan-20-on) -, progesteron a estradiolbyly stanoveny u 138 těhotných žen. Byl navržen model stabilizujícího vlivu pregnanolonu na průběh těhotenství a opačně působícího vlivu estradiolu.

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Project
<a href="/en/project/NB7070" target="_blank" >NB7070: Neuroactive steroids, imunomodulatory steroids and ergosteroids in pregnancy and around parturition.</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2005
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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