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Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F07%3A00091938" target="_blank" >RIV/61388963:_____/07:00091938 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma

  • Original language description

    On a group of 730 patients with RCC we examined expression of CAIX antigen. CAIX was present in 97% of tumors, 22.3% tumors exhibited low expression. Univariately, low CAIX expression was associated with increased risk of RCC death compared to high expression (risk ratio 1.65, p<0.001). However, low CAIX was not an independent marker after adjusting for nuclear grade or coagulative tumor necrosis.

  • Czech name

    Anhydrasa kyseliny uhličité CAIX není nezávislým prognostickým znakem pro pacienty s adenokarcinomem ledvin

  • Czech description

    Na souboru 730 pacientů s adenokarcinomem ledviny jsme zjišťovali souvislost mezi intensitou exprese antigenu CAIX a rizikem smrti. CAIX jsme nalezli v 97% nádorů, v 22.3% byla exprese nízká. Ta byla asociována se zvýšeným risikem smrti v jednostranném srovnání s vysokou expresí (risikový factor 1.65, p<0.001). Není však nezávislým znakem po zvážení jiných histopatologických parametrů.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Clinical Oncology

  • ISSN

    0732-183X

  • e-ISSN

  • Volume of the periodical

    25

  • Issue of the periodical within the volume

    30

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    4757-4764

  • UT code for WoS article

  • EID of the result in the Scopus database