Azacytosine Derivatives Useful as Antiviral Agents
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F10%3A00356428" target="_blank" >RIV/61388963:_____/10:00356428 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Azacytosine Derivatives Useful as Antiviral Agents
Original language description
1-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine (HPMP-5-azaC), its cyclic form and a series of ester prodrugs were prepared as a new type of antiviral agents active against all species of DNA viruses in vitro and in vivo. HPMP-5-azaC showed a2- to 16-fold higher antiviral selectivity index compared to cidofovir.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/1M0508" target="_blank" >1M0508: New Antivirals and Antineoplastics</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
EP1966226
Publisher
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Publisher name
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Place of publication
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Publication country
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Date of acceptance
Nov 10, 2010
Owner name
Ústav organické chemie a biochemie AV ČR, v. v. i. - K.U. Leuven Research and Development, Leuven, BE
Method of use
B - Výsledek je využíván orgány státní nebo veřejné správy
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence