RNASTAR: An RNA STructural Alignment Repository that provides insight into the evolution of natural and artificial RNAs
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F12%3A00377926" target="_blank" >RIV/61388963:_____/12:00377926 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1261/rna.032052.111" target="_blank" >http://dx.doi.org/10.1261/rna.032052.111</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1261/rna.032052.111" target="_blank" >10.1261/rna.032052.111</a>
Alternative languages
Result language
angličtina
Original language name
RNASTAR: An RNA STructural Alignment Repository that provides insight into the evolution of natural and artificial RNAs
Original language description
Automated RNA alignment algorithms often fail to recapture the essential conserved sites that are critical for function. To assist in the refinement of these algorithms, we manually curated a set of 148 alignments with a total of 9600 unique sequences, in which each alignment was backed by at least one crystal or NMR structure. These alignments included both naturally and artificially selected molecules. We used principles of isostericity to improve the alignments from an average of 83%-94% isosteric base pairs. We expect that this alignment collection will assist in a wide range of benchmarking efforts and provide new insight into evolutionary principles governing change in RNA structural motifs. The improved alignments have been contributed to the Rfam database.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ME09019" target="_blank" >ME09019: Theoretical investigation of RNA structure, dynamics and function and their relationship.</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
R N A
ISSN
1355-8382
e-ISSN
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Volume of the periodical
18
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
1319-1327
UT code for WoS article
000305349000002
EID of the result in the Scopus database
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