The Effects of Pterostilbene on Neutrophil Activity in Experimental Model of Arthritis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F13%3A00399813" target="_blank" >RIV/61388963:_____/13:00399813 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/13:00399813
Result on the web
<a href="http://dx.doi.org/10.1155/2013/106041" target="_blank" >http://dx.doi.org/10.1155/2013/106041</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2013/106041" target="_blank" >10.1155/2013/106041</a>
Alternative languages
Result language
angličtina
Original language name
The Effects of Pterostilbene on Neutrophil Activity in Experimental Model of Arthritis
Original language description
It has been demonstrated that pterostilbene inhibits reactive oxygen species production in neutrophils in vitro. However, little is known about its effects on neutrophils during inflammation in vivo. In this study, the effect of pterostilbene on neutrophil activity was investigated in experimental arthritis model. Lewis rats were injected by a single intradermal injection of heat-killed Mycobacterium butyricum in Freund's adjuvant to develop arthritis. Another group of arthritic animals received pterostilbene 30mg/kg, daily, p.o. The number and activity of neutrophils in blood were measured on a weekly basis during the whole experiment. Moreover, the total radical trapping potential in plasma was measured at the end of the experiment. In the pterostilbene treated arthritic group, the treatment significantly lowered the number of neutrophils in blood on days 14 and 21 without significant downregulation of neutrophil oxidative burst. Pterostilbene nonsignificantly increased total radical
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EI - Biotechnology and bionics
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BIOMED RESEARCH INTERNATIONAL
ISSN
2314-6133
e-ISSN
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Volume of the periodical
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Issue of the periodical within the volume
106041
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
"106041/1"-"106041/7"
UT code for WoS article
000325580600001
EID of the result in the Scopus database
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