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Transition-Metal-Free Coupling Reaction of Dithiocarbamates with Indoles: C-S Bond Formation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F18%3A00490830" target="_blank" >RIV/61388963:_____/18:00490830 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1021/acs.joc.8b00206" target="_blank" >http://dx.doi.org/10.1021/acs.joc.8b00206</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1021/acs.joc.8b00206" target="_blank" >10.1021/acs.joc.8b00206</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Transition-Metal-Free Coupling Reaction of Dithiocarbamates with Indoles: C-S Bond Formation

  • Original language description

    A one-pot three-component route for the direct introduction of dithiocarbamates into indoles using a C-H sulfenylation strategy mediated by molecular iodine is disclosed. Various indole derivatives including 1-methylindole, 2-methylindole, 3-methylindole, and 5-substituted indoles were applied successfully in this protocol to afford diverse indole-dithiocarbamates containing the dithiocarbamate group on the position two or three in good to high yields. The reactions do not require transition metals or disulfiram but use an environmentally benign solvent and simple commercially available starting materials.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10401 - Organic chemistry

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Organic Chemistry

  • ISSN

    0022-3263

  • e-ISSN

  • Volume of the periodical

    83

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    5778-5783

  • UT code for WoS article

    000432900800044

  • EID of the result in the Scopus database

    2-s2.0-85047250370