Bioorthogonal Chemistry in Cellular Organelles
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F24%3A00579956" target="_blank" >RIV/61388963:_____/24:00579956 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22310/24:43929231 RIV/60461373:22330/24:43929231
Result on the web
<a href="https://doi.org/10.1007/s41061-023-00446-5" target="_blank" >https://doi.org/10.1007/s41061-023-00446-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s41061-023-00446-5" target="_blank" >10.1007/s41061-023-00446-5</a>
Alternative languages
Result language
angličtina
Original language name
Bioorthogonal Chemistry in Cellular Organelles
Original language description
While bioorthogonal reactions are routinely employed in living cells and organisms, their application within individual organelles remains limited. In this review, we highlight diverse examples of bioorthogonal reactions used to investigate the roles of biomolecules and biological processes as well as advanced imaging techniques within cellular organelles. These innovations hold great promise for therapeutic interventions in personalized medicine and precision therapies. We also address existing challenges related to the selectivity and trafficking of subcellular dynamics. Organelle-targeted bioorthogonal reactions have the potential to significantly advance our understanding of cellular organization and function, provide new pathways for basic research and clinical applications, and shape the direction of cell biology and medical research.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Topics in Current Chemistry
ISSN
2365-0869
e-ISSN
2364-8961
Volume of the periodical
382
Issue of the periodical within the volume
1
Country of publishing house
CH - SWITZERLAND
Number of pages
52
Pages from-to
2
UT code for WoS article
001124697200001
EID of the result in the Scopus database
2-s2.0-85179902216