Rpg1p/eIF3a associates with mitrochondria in saccharomyces cerevisiae

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F04%3A00100376" target="_blank" >RIV/61388971:_____/04:00100376 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Rpg1p/eIF3a associates with mitrochondria in saccharomyces cerevisiae
Original language description
RPG1/TIF32, the essential gene of Saccharomyces cerevisiae, encodes eIF3a subunit of the translation initiation factor 3. We show here that both temperature sensitive mutant of Rpg1 strongly differ in their distribution at permissive temperature, distribution of the Rpg1-1-GFP fusion is cytosolic, the fusion protein Rpg1-2-GFP was accumulated in large cytosolic aggregates. Using the life image analysis with confocal laser scanning microscope we found that these granules could be inherited to daughter cells and obviously associate with mitochondria.
Czech name
Rpg1p/eIF3a se spojuje s mitochondriemi v Saccharomyces cerevisiae
Czech description
RPG1/TIF32 je esenciálním genem kvasinky S.cerevisiae. Ukázali jsme, že ts mutace rpg1-1 a rpg1-2 ovlivnují distribuci tohoto proteinu. Zvláště intragenově značená verse mutantu rpg1-2 se akumuluje v granulích i v permisivní teplotě a tyto granule asociují s mitochondriemi a jsou děděny.

Project
<a href="/en/project/GA204%2F02%2F1424" target="_blank" >GA204/02/1424: Role of cytoskeletal interactions of the translation initiation factor eIF3 in yeast morphogenesis</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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