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Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83:K24:H31)

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F05%3A00022215" target="_blank" >RIV/61388971:_____/05:00022215 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83:K24:H31)

  • Original language description

    Colonization by the commensal Escherichia coli strain A0 34/86 (O83 : K24 : H31) has proved to be safe and efficient in the prophylaxis and treatment of nosocomial infections and diarrhoea of preterm and newborn infants in Czech paediatric clinics over the past three decades. In searching for traits contributing to this beneficial effect related to the gut colonization capacity of the strain, the authors have analysed its genome by DNA-DNA hybridization to E. coli K-12 (MG1655) genomic DNA arrays and to'Pathoarrays', as well as by multiplex PCR, bacterial artificial chromosome (BAC) library cloning and shotgun sequencing. Four hundred and ten E. coli K-12 ORFs were absent from A0 34/86, while 72 out of 456 genes associated with pathogenicity islands of E. coli and Shigella were also detected in E. coli A0 34/86

  • Czech name

    Charakterizace flexibilní složky genomu komensálního kmene Escherichia coli A0 34/86 (O83 : K24 : H31)

  • Czech description

    Kmen Escherichia coli A0 34/86 (O83 : K24 : H31) je komensální bakterie koužívaná ke kolonizaci střeva u rizikových nedonošenců a novorozenců. Ve snaze charakterizovat geny odpovídající za unikátní probiotické vlastnosti kmene jsme provedli částečnou sekvenaci jeho genomu. Přitom jsme identifikovali řadu potenciálních tzv. ?faktorů virulence?. Práce ukazuje jak tenká hranice je mezi faktory odpovědnými za schopnost kolonizace hostile a virulenci

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/IBS5020311" target="_blank" >IBS5020311: Vaccines for induction of mucosal and systemic immunity</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Microbiology

  • ISSN

    0001-9539

  • e-ISSN

  • Volume of the periodical

    2005

  • Issue of the periodical within the volume

    -

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    14

  • Pages from-to

    385-398

  • UT code for WoS article

  • EID of the result in the Scopus database