Ovarian hyperstimulation syndrome biomarker(s) search in human follicular fluid
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F09%3A00338300" target="_blank" >RIV/61388971:_____/09:00338300 - isvavai.cz</a>
Alternative codes found
RIV/67985904:_____/09:00338300
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Ovarian hyperstimulation syndrome biomarker(s) search in human follicular fluid
Original language description
Ovarian hyperstimulation syndrome (OHSS) is a serious complication of in vitro fertilisation therapy using hormonal stimulation of ovaries. Current diagnosis is not sufficient and could be significantly improved if a protein biomarker(s) could be identified in patient follicular fluid (HFF). In search for new potential diagnostic and prognostic biomarker(s) of OHSS we have used a combination of immunoaffinity depletion, 2-D LC and 2-DE to obtain 2D protein profiles of HFF from OHSS positive and OHSS negative women. The protein maps were evaluated using software tools and protein spots or bands significantly increased or decreased in HFF of OHSS positive and OHSS negative women were identified using MS. In total, we identified 20 proteins and 3 of themwere shared between two different 2D technologies. Most of the identified proteins belong to different functional groups including the complement cascade, transport, blood coagulation, acute phase response and inflammation.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
FK - Gynaecology and obstetrics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/1QS500450568" target="_blank" >1QS500450568: Female gametes - regulation of their meiotic and developmental competence and possibilities of its practical application</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
3rd Central and Eastern Proteomics Conference, 2009
ISBN
978-963-9319-99-8
ISSN
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e-ISSN
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Number of pages
1
Pages from-to
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Publisher name
Hungarian proteomic society
Place of publication
Budapest
Event location
Budapešť
Event date
Oct 6, 2009
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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