Dissociation of nystatin and amphotericin analogues: characterization of minor anti-fungal macrolides

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F10%3A00340845" target="_blank" >RIV/61388971:_____/10:00340845 - isvavai.cz</a>

Alternative codes found

RIV/61388971:_____/10:00341256

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Dissociation of nystatin and amphotericin analogues: characterization of minor anti-fungal macrolides

Original language description

Tandem mass spectrometry combined with Fourier transform ion cyclotron resonance (FTICR) has been the basis for rationalizing the fragmentation mechanisms of antifungal macrolides nystatin A1, amphotericin B and pimaricin. The positive ion mass spectra were not informative, however, the dissociation of deprotonated molecules led to structurally significant ring-opened fragments. Using this approach of tandem FTICR mass spectrometry (MS/MS) and electrospray ionization (ESI) coupled with high-performanceliquid chromatography (HPLC), eleven macrolide natural analogues or degradation products were characterized in the nystatin mixture

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

<a href="/en/project/LC07017" target="_blank" >LC07017: Oncoproteomics Centre</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Mass Spectrometry

ISSN

1469-0667

e-ISSN

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Volume of the periodical

16

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

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UT code for WoS article

000274290200008

EID of the result in the Scopus database

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