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Deregulation of expression of virulence factors in fur mutants of Pseudomonas aeruginosa

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F10%3A00357396" target="_blank" >RIV/61388971:_____/10:00357396 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Deregulation of expression of virulence factors in fur mutants of Pseudomonas aeruginosa

  • Original language description

    Increased production of the virulent factors was found in the fur mutant strains of Pseudomonas aeruginosa FPA12 and FF13 even under conditions of their full repression by FeIII. The mutants overproduce specific receptors for pyoverdine (FpvA) and pyochelin (FptA) in iron-deplete medium. Upon FeIII supplementation into the medium (60?M FeCl3) the Fur phenotype of fur mutants was studied. Transcription profiling of the fur mutant strain FPA12 in response of iron was performed with focus on the expressionof Fur-regulated genes coding for virulence factors

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů