The secretome of facultative intracelullar bacterium Francisella tularensis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F05%3A00001388" target="_blank" >RIV/60162694:G44__/05:00001388 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The secretome of facultative intracelullar bacterium Francisella tularensis
Original language description
The gram negative coccobacillus, Francisella tularensis, is a facultative intracellular bacterial pathogen which naturally causes the zoonotic disease tularemia.Recently, Francisella pathogenicity island (FPI) encoding several genes required for both intracellular survival in macrophages and virulence in the mouse infection model was described (Nano et al., 2004). Furthermore, gene clusters encoding proteins required for either a type I (transporters containing ATP-binding casettes) or a type II secretion systems (type IV pili system) were detected in F. tularensis genome. The key factor for the survival the bacterium in hostile intracellular milieu is then its ability of iron acquisition. From this point of view Fur protein and a number of genes thatmay be regulated by Fur were predicted in genome of F. tularensis SCHU S4. The aim of this work is the analysis of alteration of culture filtrate protein patterns of Francisella tularensis subsp. holarctica strain LVS induced by iron rest
Czech name
Sekretom fakultativně intracelulární bakterie Francisella tularensis
Czech description
Sekretom fakultativně intracelulární bakterie Francisella tularensis.
Classification
Type
D - Article in proceedings
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2005
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
New frontiers in the research of PhD students, Conference of Medical Schools in the Czech and Slovak Republics
ISBN
80-239-6102-0
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
77-81
Publisher name
Astraprint
Place of publication
Hradec Králové
Event location
Hradec Králové
Event date
Dec 9, 2005
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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