The enigma of the lower gut-associated lymphoid tissue (GALT)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F13%3A00425461" target="_blank" >RIV/61388971:_____/13:00425461 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1189/jlb.0313120" target="_blank" >http://dx.doi.org/10.1189/jlb.0313120</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1189/jlb.0313120" target="_blank" >10.1189/jlb.0313120</a>
Alternative languages
Result language
angličtina
Original language name
The enigma of the lower gut-associated lymphoid tissue (GALT)
Original language description
Review of specialized hind-gut lymphoid tissue, and its necessity for systemic B cell development/diversification early in life. Artiodactyls possess GALT that appears in fetal life and is located at the extreme end of the ileum. These IPP contain mostlyB cells and involute early in postnatal life. Rabbits have a similarly located lymphoid organ, called the sacculus rotundus. Studies in sheep and rabbits have led to the concept that the lower hindgut GALT represents primary lymphoid tissue for B cellsand is necessary for normal B cell development, analogous to the bursa of Fabricius. This review traces the history of the observations and theories that have led to the existing concept concerning the role of lower GALT. We then review recent data frompiglets with resected IPP that challenges the concept that the IPP is primary B cell lymphoid tissue and that artiodactyls and rabbits are members of the GALT group in the same context as gallinaceous birds. Eliminating the IPP as the pri
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Leukocyte Biology
ISSN
0741-5400
e-ISSN
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Volume of the periodical
94
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
259-270
UT code for WoS article
000329744300007
EID of the result in the Scopus database
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