Characterization of N-Demethyl lincosamide Methyltransferases LmbJ and CcbJ
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F13%3A00425635" target="_blank" >RIV/61388971:_____/13:00425635 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/cbic.201300389" target="_blank" >http://dx.doi.org/10.1002/cbic.201300389</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/cbic.201300389" target="_blank" >10.1002/cbic.201300389</a>
Alternative languages
Result language
angličtina
Original language name
Characterization of N-Demethyl lincosamide Methyltransferases LmbJ and CcbJ
Original language description
Two putative methyltrasferases LmbJ and CcbJ from the biosynthesis of lincosamide antibiotics lincomycin and celesticetin respectively, were characterized biochemicalla and confirmed do possess a homooligomeric, probably hexameric quaternary structure. LmbJ was confirmed to convert N-demethyl lincomycin. CcbJ is able to catalyze the same reaction with comparable efficiency, indicating tha its substrate specificity is somewhat relaxed.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chembiochem
ISSN
1439-4227
e-ISSN
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Volume of the periodical
14
Issue of the periodical within the volume
17
Country of publishing house
DE - GERMANY
Number of pages
4
Pages from-to
2259-2262
UT code for WoS article
000330181300006
EID of the result in the Scopus database
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