Assessing immunological properties of biomaterials for bone regeneration applications

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F14%3A00457093" target="_blank" >RIV/61388971:_____/14:00457093 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1533/9780857098104.2.324" target="_blank" >http://dx.doi.org/10.1533/9780857098104.2.324</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1533/9780857098104.2.324" target="_blank" >10.1533/9780857098104.2.324</a>

Result language
angličtina
Original language name
Assessing immunological properties of biomaterials for bone regeneration applications
Original language description
Regeneration of bone defects using biomaterials is an alternative to transplantation of autologous graft. The biomaterials must meet the requirements of functionality and should be bio- and immunocompatible, as any undesirable inflammatory or immune response induced by the biomaterial could worsen the outcome of the treatment. The chapter first briefly summarizes the course of acute and chronic inflammation and the key mechanisms of induction of specific immune response. The next part describes some options for testing biomaterial immunocompatibility, focusing on assessment of macrophage activation, dendritic cell maturation, and on in vivo subcutaneous implantation model.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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