Catabolism of Phenol and Its Derivatives in Bacteria: Genes, Their Regulation, and Use in the Biodegradation of Toxic Pollutants

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F15%3A00450938" target="_blank" >RIV/61388971:_____/15:00450938 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/bs.aambs.2015.06.002" target="_blank" >http://dx.doi.org/10.1016/bs.aambs.2015.06.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/bs.aambs.2015.06.002" target="_blank" >10.1016/bs.aambs.2015.06.002</a>

Result language

angličtina

Original language name

Catabolism of Phenol and Its Derivatives in Bacteria: Genes, Their Regulation, and Use in the Biodegradation of Toxic Pollutants

Original language description

Phenol and its derivatives (alkylphenols, halogenated phenols, nitrophenols) are natural or man-made aromatic compounds that are ubiquitous in nature and in human-polluted environments. Many of these substances are toxic and/or suspected of mutagenic, carcinogenic, and teratogenic effects. Bioremediation of the polluted soil and water using various bacteria has proved to be a promising option for the removal of these compounds. In this review, we describe a number of peripheral pathways of aerobic and anaerobic catabolism of various natural and xenobiotic phenolic compounds, which funnel these substances into a smaller number of central catabolic pathways. Finally, the metabolites are used as carbon and energy sources in the citric acid cycle. We provide here the characteristics of the enzymes that convert the phenolic compounds and their catabolites, show their genes, and describe regulatory features. The genes, which encode these enzymes, are organized on chromosomes and plasmids of the natural bacterial degraders in various patterns. The accumulated data on similarities and the differences of the genes, their varied organization, and particularly, an astonishingly broad range of intricate regulatory mechanism may be read as an exciting adventurous book on divergent evolutionary processes and horizontal gene transfer events inscribed in the bacterial genomes. In the end, the use of this wealth of bacterial biodegradation potential and the manipulation of its genetic basis for purposes of bioremediation is exemplified. It is envisioned that the integrated high-throughput techniques and genome-level approaches will enable us to manipulate systems rather than separated genes, which will give birth to systems biotechnology.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10606 - Microbiology

Project

<a href="/en/project/TA04021212" target="_blank" >TA04021212: Development of technology for removal of organic substances with a focus on substances known in coking technology as "tarry substance" from coking plant sewage.</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Advances in Applied Microbiology

ISSN

0065-2164

e-ISSN

—

Volume of the periodical

93

Issue of the periodical within the volume

2015

Country of publishing house

GB - UNITED KINGDOM

Number of pages

54

Pages from-to

107-160

UT code for WoS article

000405620900004

EID of the result in the Scopus database

2-s2.0-84945539104