Biodegradation of phenol and its derivatives by engineered bacteria: current knowledge and perspectives
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F17%3A00489597" target="_blank" >RIV/61388971:_____/17:00489597 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s11274-017-2339-x" target="_blank" >http://dx.doi.org/10.1007/s11274-017-2339-x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11274-017-2339-x" target="_blank" >10.1007/s11274-017-2339-x</a>
Alternative languages
Result language
angličtina
Original language name
Biodegradation of phenol and its derivatives by engineered bacteria: current knowledge and perspectives
Original language description
Biodegradation of phenolic compounds is a promising alternative to physical and chemical methods used to remove these toxic pollutants from the environment. The ability of various microorganisms to metabolize phenol and its derivatives (alkylphenols, nitrophenols and halogenated derivatives) has therefore been intensively studied. Knowledge of the enzymes catalyzing the individual reactions, the genes encoding these enzymes and the regulatory mechanisms involved in the expression of the respective genes in bacteria serves as a basis for the development of more efficient degraders of phenols via genetic engineering methods. Engineered bacteria which efficiently degrade phenolic compounds were constructed in laboratories using various approaches such as cloning the catabolic genes in multicopy plasmids, the introduction of heterologous genes or broadening the substrate range of key enzymes by mutagenesis. Efforts to apply the engineered strains in in situ bioremediation are problematic, since engineered strains often do not compete successfully with indigenous microorganisms. New efficient degraders of phenolic compounds may be obtained by complex approaches at the organism level, such as genome shuffling or adaptive evolution. The application of these engineered bacteria for bioremediation will require even more complex analysis of both the biological characteristics of the degraders and the physico-chemical conditions at the polluted sites.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/TA04021212" target="_blank" >TA04021212: Development of technology for removal of organic substances with a focus on substances known in coking technology as "tarry substance" from coking plant sewage.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
World Journal of Microbiology and Biotechnology
ISSN
0959-3993
e-ISSN
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Volume of the periodical
33
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
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UT code for WoS article
000411062900013
EID of the result in the Scopus database
2-s2.0-85029022047