The Absence of Pupylation (Prokaryotic Ubiquitin-Like Protein Modification) Affects Morphological and Physiological Differentiation in Streptomyces coelicolor

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F15%3A00451193" target="_blank" >RIV/61388971:_____/15:00451193 - isvavai.cz</a>

Alternative codes found

RIV/44555601:13440/15:43886778

Result on the web

<a href="http://dx.doi.org/10.1128/JB.00591-15" target="_blank" >http://dx.doi.org/10.1128/JB.00591-15</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1128/JB.00591-15" target="_blank" >10.1128/JB.00591-15</a>

Result language

angličtina

Original language name

The Absence of Pupylation (Prokaryotic Ubiquitin-Like Protein Modification) Affects Morphological and Physiological Differentiation in Streptomyces coelicolor

Original language description

rotein turnover is essential in all living organisms for the maintenance of normal cell physiology. In eukaryotes, most cellular protein turnover involves the ubiquitin-proteasome pathway, in which proteins tagged with ubiquitin are targeted to the proteasome for degradation. In contrast, most bacteria lack a proteasome but harbor proteases for protein turnover. However, some actinobacteria, such as mycobacteria, possess a proteasome in addition to these proteases. A prokaryotic ubiquitination-like tagging process in mycobacteria was described and was named pupylation: proteins are tagged with Pup (prokaryotic ubiquitin-like protein) and directed to the proteasome for degradation. We report pupylation in another actinobacterium, Streptomyces coelicolor. Both the morphology and life cycle of Streptomyces species are complex (formation of a substrate and aerial mycelium followed by sporulation), and these bacteria are prolific producers of secondary metabolites with important medicinal a

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Bacteriology

ISSN

0021-9193

e-ISSN

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Volume of the periodical

197

Issue of the periodical within the volume

21

Country of publishing house

US - UNITED STATES

Number of pages

12

Pages from-to

3388-3399

UT code for WoS article

000362559300003

EID of the result in the Scopus database

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