Stratification of yeast cells during chronological aging by size points to the role of trehalose in cell vitality

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F16%3A00462514" target="_blank" >RIV/61388971:_____/16:00462514 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s10522-015-9625-5" target="_blank" >http://dx.doi.org/10.1007/s10522-015-9625-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10522-015-9625-5" target="_blank" >10.1007/s10522-015-9625-5</a>

Result language
angličtina
Original language name
Stratification of yeast cells during chronological aging by size points to the role of trehalose in cell vitality
Original language description
Cells of the budding yeast Saccharomyces cerevisiae undergo a process akin to differentiation during prolonged culture without medium replenishment. Various methods have been used to separate and determine the potential role and fate of the different cell species. We have stratified chronologically-aged yeast cultures into cells of different sizes, using centrifugal elutriation, and characterized these subpopulations physiologically. We distinguish two extreme cell types, very small (XS) and very large (L) cells. L cells display higher viability based on two separate criteria. They respire much more actively, but produce lower levels of reactive oxygen species (ROS).
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Project
<a href="/en/project/LH13049" target="_blank" >LH13049: Connection of mitochondrial activity and morphology during yeast aging</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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