Lincosamide derivatives, preparation and use thereof as antimicrobial agent
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F20%3A00617028" target="_blank" >RIV/61388971:_____/20:00617028 - isvavai.cz</a>
Result on the web
<a href="https://ppubs.uspto.gov/dirsearch-public/print/downloadBasicPdf/10822366?requestToken=eyJzdWIiOiJlNDlmMzdlZi1mYmYwLTQwM2EtOWE4Ni1iNDVkNjllM2M4MzIiLCJ2ZXIiOiIwNjY4M2RlNS0wYTlhLTQ5MmEtYWY2NC02MTcwYTNhMTBlYzUiLCJleHAiOjB9" target="_blank" >https://ppubs.uspto.gov/dirsearch-public/print/downloadBasicPdf/10822366?requestToken=eyJzdWIiOiJlNDlmMzdlZi1mYmYwLTQwM2EtOWE4Ni1iNDVkNjllM2M4MzIiLCJ2ZXIiOiIwNjY4M2RlNS0wYTlhLTQ5MmEtYWY2NC02MTcwYTNhMTBlYzUiLCJleHAiOjB9</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Lincosamide derivatives, preparation and use thereof as antimicrobial agent
Original language description
Lincosamides of general formula I, where R1 is selected from C2-C8 alkyl or C2-C8 alkenyl, R3 is selected from OH, O(C1-C4 alkyl), SH, S(C1-C4 alkyl) or halogen, R4 is H or C1-C3 alkyl, each of R21, R22, R23, R24, R25 is independently selected from the group consisting of H, OH, C1-C4 alkyl, C1-C4 alkenyl, C1-C4 alkynyl, halogen, O(C1-C4 alkyl), O(C1-C4 alkenyl), O(C1-C4 alkynyl), NH2, N(C1-C4 alkyl)2, N(C1-C4 alkenyl)2, N(C1-C4 alkynyl)2, and pharmaceutically acceptable salts thereof. A method of preparation thereof, in particular a biosynthetic method using newly discovered functions of celesticetin biosynthetic proteins Ccb1 and/or Ccb2. Lincosamides of general formula I are suitable for use as antibacterial and antiprotozoal substances
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/LQ1604" target="_blank" >LQ1604: BIOCEV: from Fundamental to Applied Research</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
US 10,822,366 B2
Publisher
US001 -
Publisher name
United States Patent and Trademark Office (USPTO)
Place of publication
Alexandria
Publication country
US - UNITED STATES
Date of acceptance
Nov 3, 2020
Owner name
Mikrobiologický ústav AV ČR, v. v. i.
Method of use
A - Výsledek využívá pouze poskytovatel
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence