gamma-Tubulin Complexes and Fibrillar Arrays: Two Conserved High Molecular Forms with Many Cellular Functions

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F21%3A00542216" target="_blank" >RIV/61388971:_____/21:00542216 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/2073-4409/10/4/776" target="_blank" >https://www.mdpi.com/2073-4409/10/4/776</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/cells10040776" target="_blank" >10.3390/cells10040776</a>

Result language

angličtina

Original language name

gamma-Tubulin Complexes and Fibrillar Arrays: Two Conserved High Molecular Forms with Many Cellular Functions

Original language description

Higher plants represent a large group of eukaryotes where centrosomes are absent. The functions of gamma-tubulin small complexes (gamma-TuSCs) and gamma-tubulin ring complexes (gamma-TuRCs) in metazoans and fungi in microtubule nucleation are well established and the majority of components found in the complexes are present in plants. However, plant microtubules are also nucleated in a gamma-tubulin-dependent but gamma-TuRC-independent manner. There is growing evidence that gamma-tubulin is a microtubule nucleator without being complexed in gamma-TuRC. Fibrillar arrays of gamma-tubulin were demonstrated in plant and animal cells and the ability of gamma-tubulin to assemble into linear oligomers/polymers was confirmed in vitro for both native and recombinant gamma-tubulin. The functions of gamma-tubulin as a template for microtubule nucleation or in promoting spontaneous nucleation is outlined. Higher plants represent an excellent model for studies on the role of gamma-tubulin in nucleation due to their acentrosomal nature and high abundancy and conservation of gamma-tubulin including its intrinsic ability to assemble filaments. The defining scaffolding or sequestration functions of plant gamma-tubulin in microtubule organization or in nuclear processes will help our understanding of its cellular roles in eukaryotes.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10601 - Cell biology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cells

ISSN

2073-4409

e-ISSN

2073-4409

Volume of the periodical

10

Issue of the periodical within the volume

4

Country of publishing house

CH - SWITZERLAND

Number of pages

14

Pages from-to

776

UT code for WoS article

000642853900001

EID of the result in the Scopus database

2-s2.0-85105212260